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Image Search Results
Journal: Frontiers in Nutrition
Article Title: Prevention of high-fat/high-sugar diet-induced type 2 diabetes mellitus-associated non-alcoholic fatty liver disease in rats with fermented and raw Rosa roxburghii Tratt (Cili) juice
doi: 10.3389/fnut.2025.1584551
Figure Lengend Snippet: Expression analyses of transcription or protein levels of selected genes. (A) Expression analyses of selected genes by qRT–PCR. The data represent the means ± SDs from six biological replicates with three technical replicates. (B–D) FCJ/RCJ upregulated ABCC3, IDI1, and APOA2 expression in the liver. FCJ and RCJ significantly upregulated hepatic ABCC3 (B) and IDI1 (C) expression, and RCJ significantly upregulated hepatic APOA2 (D) expression in T2DM rats. The data represent the means ± SDs from three biological replicates with three technical replicates. * p < 0.05, *** p < 0.001, **** p < 0.0001.
Article Snippet: The western blotting antibodies used included APOA2 (BM5624, BOSTER, China),
Techniques: Expressing, Quantitative RT-PCR
Journal: International journal of biological sciences
Article Title: Deficiency of Epithelial PIEZO1 Alleviates Liver Steatosis Induced by High-Fat Diet in Mice.
doi: 10.7150/ijbs.102906
Figure Lengend Snippet: Figure 3. PIEZO1 ablation downregulated FXR-FGF15/19 signaling pathway in IEC and reduced FGF15 secretion. mRNA levels of (A) Fxr, (B) Shp and (C) Fgf15 in ileum epithelium, n=6/group. (D) Western blot of FXR and SHP in ileum epithelium, n=6/group. (E) FGF15 concentration in ileum epithelium, n=6/group. (F) FGF15 concentration in portal vein, n=6/group. (G) FGF15 concentration in serum, n=6/group. mRNA levels of (H) Fxr, (I) Shp in liver, n=6/group. (J) Western blot of FXR and SHP in liver, n=6/group. (K) mRNA levels of genes associated with BAs synthesis in liver, n=6/group. (L) CYP7A1 protein level in liver by ELISA, n=6/group. Data are presented as mean ± sem. *P < 0.05, **P < 0.01, ***P < 0.001. ns, not significant.
Article Snippet: FGF15 and
Techniques: Western Blot, Concentration Assay, Enzyme-linked Immunosorbent Assay